Regular solution theory for nonlinear composition dependency of enantioselectivity by mixed micelle

Mixtures of chiral and achiral building blocks supramolecules exhibit interesting cooperative properties, as indicated by the nonlinear relationship between properties mole fraction blocks. However, composition dependence recognition capability spherical mixed micelles is poorly understood. This study hypothesized that phenomenon could be described regular solution theory reported to able describe critical micelle concentration (CMC) partition coefficients interaction parameters ? B, respectively. The CMC surfactant in were simulated using varying two surfactants. Equations enantioselectivity are newly derived this work, dependency on B was studied detail. applied micellar electrokinetic chromatography (MEKC) for first time. It found formula can MEKC. coefficient determined MEKC agreement with versus relation, which previously reported.